{"id":21,"date":"2013-11-27T01:32:06","date_gmt":"2013-11-27T01:32:06","guid":{"rendered":"http:\/\/moraeslab.com\/cmed\/?page_id=21"},"modified":"2026-01-05T06:07:28","modified_gmt":"2026-01-05T06:07:28","slug":"publications","status":"publish","type":"page","link":"https:\/\/moraeslab.com\/cmed\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"

Please note: Digital copies provided for personal use only.
\nCitation information available via Google Scholar<\/a>.<\/p>\n

Journal articles:<\/strong><\/h2>\n

\u00a7, *\u00a0 indicates equal authorship<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
<\/td>\n[94].<\/td>\nHeart-On-a-Chip with Integrated Ultrasoft Mechanosensors for Continuous Measurement of Cell- and Tissue-scale Contractility
\n<\/strong>Mousavi, A., Boghdady, C-M<\/u>., Cui, S., Rostami, S.<\/u>, Shakeri, A., Rafatian, N., Aurousseau, M., Andelfinger, G., Radisic, M., Moraes, C., Savoji, H.*,\u00a0Small<\/em><\/span>(in press) [pdf] [SI] [link]
\n<\/strong><\/td>\n<\/tr>\n
<\/td>\n[93].<\/td>\nBacterial bioluminescence shows nanotexturing does not enhance antibacterial efficacy of zinc oxide membrane coatings
\n<\/strong>Lin, N., McKay, G., Nguyen, D., Tufenkji, N.*, Moraes, C.* RSC Applied Interfaces<\/em> (2025) [pdf] [SI] [link]
\n<\/strong><\/td>\n<\/tr>\n
<\/td>\n[92].<\/td>\nInternal Delivery and Transport within Cellular Aggregates via Perfusable Glass-Sheathed Hydrogel Microtubes
\n<\/strong>Li, C., Kalashnikov, N., Moraes, C.*,\u00a0Langmuir <\/em><\/span>41, 36, 24295\u201324306 (2025) [pdf] [link]
\n<\/strong><\/td>\n<\/tr>\n
<\/td>\n[91].<\/td>\nMicropocket-based differentiation system to streamline and scale stem cell-derived pancreatic islet production
\n<\/strong>O\u2019Brien, S., Li, C., Trana, R., Hoesli, C.A.*, Moraes, C.*\u00a0ACS Biomaterials Science and Engineering<\/em><\/span> (2025) [pdf] [SI] [link<\/a>]
\n<\/strong><\/td>\n<\/tr>\n
<\/td>\n[90].<\/td>\nInvasive phenotypes of triple-negative breast cancer-associated fibroblasts are mechanosensitive, AhR-dependent and correlate with disease state
\n<\/strong>Brewer, G., Savage, P., Fortier, A-M., Zhao, H., Pacis, A., Wang, Y-C., Zuo, D., de Nobrega, M., Pedersen, A., \u00a0Cassel de Camps, C., Souleimanova, M., Mu\u00f1oz Ramos, V., Ragoussis, I., Park, M.*, Moraes, C.*,\u00a0Acta Biomaterialia<\/em><\/span> (2025) [pdf] [SI] [link<\/a>]
\n<\/strong><\/td>\n<\/tr>\n
<\/td>\n[89].<\/td>\nIntegrating miniaturized turbines into microfluidic droplet generating systems for scalable microgel production
\n<\/strong>Campbell, B.E., Zhang, K., Shi, A., Rostami, S., Pioche-Lee, D., Li, C., Leblond, A., Forigua, A., Boghdady, C-M., Moraes, C.*, Lesher-Perez, S-C.*, ACS Applied Bio Materials<\/em><\/span> (2025) [pdf] [SI] [link<\/a>]. News coverage – University of Michigan<\/a>
\n<\/strong><\/td>\n<\/tr>\n
<\/td>\n[88].<\/td>\nEmerging views of biomechanics via embedded sensors in model tissues: pathways to the clinic
\n<\/strong>Forigua, A., Campbell, B.E., Moraes, C.*, Current Opinion in Biomedical Engineering<\/em><\/span> (2025) [pdf] [link<\/a>]
\n<\/strong><\/td>\n<\/tr>\n
<\/td>\n[87].<\/td>\nMicrofabricated dynamic brain organoid cocultures to assess the effects of surface geometry on assembloid formation
\n<\/strong>Cassel de Camps, C.,Rostami, S., Xu, V., Li, C., Lepine, P., Durcan, T.M., Moraes, C.*, Biotechnology Journal<\/em><\/span> 19:2400070 (2024) [pdf] [link<\/a>]
\n<\/strong><\/td>\n<\/tr>\n
<\/td>\n[86].<\/td>\nDirected biomechanical compressive forces enhance placental trophoblast fusion<\/strong>
\nParameshwar, P.K., Chen, L., Arnauts, K., Jiang, J., Rostami, S., Campbell, B.E., Lu, H., Rosenzweig, D.H., Vaillancourt, C., Moraes, C.*, Scientific Reports<\/em><\/span>, DOI: 10.1038\/s41598-024-61747-3 (2024) [O] [link (OA)<\/a>]<\/td>\n<\/tr>\n
<\/td>\n[85].<\/td>\n3D Bioprinting of Food Grade Hydrogel infused with Living Pleurotus ostreatus<\/em> mycelium in Non-Sterile Conditions
\n<\/strong>Lin, N.<\/u>, Taghizadehmakoei, A., Polovina, L, McLean, I., Santana-Martinez, J.C., Naese, C., Moraes, C., Hallam S.J.*, Dahmen, J.* ACS Applied Bio Materials<\/em><\/span>, in press (2024) [pdf] [link<\/a>]<\/span>
\n<\/strong><\/td>\n<\/tr>\n
<\/td>\n[84].<\/td>\nEngineering placental trophoblast fusion: a potential role for biomechanics in syncytialization
\n<\/strong><\/strong>Parameshwar, P.K.<\/u>, Vaillancourt, C., Moraes, C.*.\u00a0 <\/strong><\/strong>Placenta<\/em><\/span>, special issue on <\/span>Trophoblast Research <\/em>(DOI: 10.1016\/j.placenta.2024.02.006)\u00a0 [pdf] [link<\/a>]<\/span><\/td>\n<\/tr>\n
<\/td>\n[83].<\/td>\nEffects of Surface Topography and Cellular Biomechanics on Nanopillar-induced bactericidal activity
\n<\/strong>Valiei, A.*, Bryche, J.F., Canva, M. Charette, P.G., Moraes, C., Hill, R.J.*, Tufenkji, N., ACS Applied Materials & Interfaces<\/em><\/span>, 16, 8, 9614\u20139625 (2024) [pdf] [link<\/a>]<\/span>
\n<\/strong><\/td>\n<\/tr>\n
<\/td>\n[82].<\/td>\nDevelopment of Photocrosslinkable Bioinks with Improved Electromechanical Properties for 3D Bioprinting of Cardiac BioRings
\n<\/strong>Mousavi A., Hedayatnia, A., Van Vliet P., Dartora, D.R., Wong N.<\/u>, Rafatian, N., Nuyt, A.M., Moraes C., Ajji A., Andelfinger G., Savoji H*.,\u00a0Applied Materials Today<\/em><\/span> 36 (2024) [pdf] [link<\/a>]<\/span>
\n<\/strong><\/td>\n<\/tr>\n
<\/td>\n[81].<\/td>\nFormulation and evaluation of PVA\/Gelatin\/Carrageenan inks for 3D printing and development of tissue-engineered heart valves
\n<\/strong>Jafari, A., Niknezhad, S.V., Kaviani, M., Saleh, W., Piet Van Vliet, P., Wong, N., Moraes, C., Ajji, A., Kadem, L., Azarpira, N., Andelfinger, G., Savoji, H., Advanced Functional Materials <\/em><\/span>(DOI: 10.1002\/adfm.202305188) [pdf] [link<\/a>]<\/span>
\n<\/strong><\/td>\n<\/tr>\n
<\/td>\n[80].<\/td>\nMonitoring Bioluminescent Pseudomonas aeruginosa on Mechano-Bactericidal Zinc Oxide Nanopillars: Implications for Self-Cleaning Antibacterial Coatings
\n<\/strong>Lin, N., McKay, G., Dao, N., Moraes, C.*, Tufenkji, N.*, ACS Applied Nano Materials<\/em><\/span>, DOI: 10.1021\/acsanm.3c03789 (2023) [pdf] [link<\/a>]<\/span><\/td>\n<\/tr>\n
<\/td>\n[79].<\/td>\npH-responsive reversible granular hydrogel based on metal-binding mussel-inspired peptides
\n<\/strong>Rammal, M., Li, C., Reeves, J., Moraes, C., Harrington, M., ACS Applied Materials and Interfaces<\/em><\/span> DOI: 10.1021\/acsami.3c06013 (2023) [pdf] [link<\/a>]<\/span><\/td>\n<\/tr>\n
<\/td>\n[78].<\/td>\nElectrochemical removal of bacteria from zinc oxide nanopillars synthesized on stainless steel
\n<\/strong>Lin, N.<\/u>, Nguyen, B., Omanovic, S., Moraes, C.*, Tufenkji, N.*, ACS Applied Engineering Materials<\/em><\/span> 1,1524\u22121534 (2023). [pdf] [link<\/a>]<\/span><\/td>\n<\/tr>\n
<\/td>\n[77].<\/td>\nSubstrate viscoelasticity affects human macrophage morphology and phagocytosis
\n<\/strong>Kalashnikov, N., Moraes, C., Soft Matter<\/em><\/span> DOI: 10.1039\/D2SM01683D (2023) [pdf] [link<\/a>]<\/td>\n<\/tr>\n
<\/td>\n[76].<\/td>\nCompressive molding of engineered tissues via smart material hydrogel devices
\n<\/strong>Cassel de Camps, C., Mok, S., Ashby, E., Li, C., Lepine, P., Durcan, T.M., Moraes, C., Lab on a Chip<\/em><\/span> DOI: 10.1039\/D3LC00007A (2023) [pdf] [link<\/a>]<\/td>\n<\/tr>\n
<\/td>\n[75].<\/td>\nUltrasoft edge-labelled hydrogel sensors reveal internal tissue stress patterns in invasive engineered tumors
\n<\/strong>Lee, W., Boghdady, C-M., Lelarge, V., Leask, R.L., McCaffrey, L., Moraes, C.*, Biomaterials<\/em><\/span> DOI: 10.1016\/j.biomaterials.2023.122073 (2023) [pdf] [link<\/a>]<\/td>\n<\/tr>\n
<\/td>\n[74].<\/td>\nIntegrating mechanical sensor readouts into organ-on-a-chip platforms
\n<\/strong>Morales, I.A., Boghdady, C-M., Campbell, B.E., Moraes, C., Frontiers in Bioengineering and Biotechnology<\/em><\/span> DOI: 10.3389\/fbioe.2022.1060895 (2023) [pdf] [link<\/a>]<\/td>\n<\/tr>\n
<\/td>\n[73].<\/td>\nDecellularized extracellular matrix: New promising and challenging biomaterials for regenerative medicine<\/strong>
\nBrown, M., Li, J., Moraes, C., Tabrizian M., Li-Jessen, N.Y., Biomaterials<\/em><\/span> DOI: 10.1016\/j.biomaterials.2022.121786 (2022) [pdf] [link<\/a>]<\/td>\n<\/tr>\n
<\/td>\n[72].<\/td>\nEngineering physical microenvironments to study innate immune cell
\nbiophysics
\n<\/strong>Kalashnikov, N., Moraes, C.,\u00a0APL Bioengineering<\/em><\/span>,\u00a0DOI: 10.1063\/5.0098578 [pdf] [link<\/a>]<\/td>\n<\/tr>\n
<\/td>\n[71].<\/td>\nEngineered models for placental toxicology: emerging approaches based on tissue decellularization
\n<\/strong>Parameshwar, P.K.*, Sagrillo-Fagundes, L.*, Portilho, N.A., Pastor, W.A., Vaillancourt, C., Moraes, C.,\u00a0Reproductive Toxicology<\/em><\/span> DOI: 10.1016\/j.reprotox.2022.07.003 (2022) [pdf] [link<\/a>]<\/td>\n<\/tr>\n
<\/td>\n[70].<\/td>\nMicrofluidic study of bacterial attachment on and detachment from zinc oxide nanopillars
\n<\/strong>Lin, N., Valiei, A., McKay, G., Nguyen, D., Tufenkji, N.*, Moraes, C.*,\u00a0ACS Biomaterials Science & Engineering<\/em><\/span>\u00a0 <\/em>DOI: 10.1021\/acsbiomaterials.2c00233 [pdf] [SI] [link<\/a>]<\/td>\n<\/tr>\n
<\/td>\n[69].<\/td>\nSurface wettability is a key feature in the mechano-bactericidal activity of nanopillars<\/strong>
\nValiei, A., Lin, N., McKay, G., Nguyen, D., Moraes, C., Hill, R.J., Tufenkji, N\u00a0ACS Applied Materials & Interfaces<\/em><\/span> DOI: 20.1021\/acsami.2c03258 [pdf] [SI] [link<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[68].<\/td>\nThe case for cancer-associated fibroblasts: essential elements in cancer drug discovery?
\n<\/strong>Brewer, G., Fortier, A-M., Park, M., Moraes, C.,\u00a0Future Drug Discovery,<\/em><\/span> doi:10.4155\/fdd-2021-0004 [pdf] [link<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[67].<\/td>\nHydrogel mechanics influence growth and development of embedded brain organoids
\n<\/strong>Cassel de Camps, C., Aslani, S., Stylianesis, N., Nami, H., Mohamed, N-V., Durcan, T.M*, Moraes, C.* ACS Applied Bio Materials<\/em><\/span> (in press) [pdf] [SI] [link<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[66].<\/td>\nAccessible, large-area, uniform dose photolithography using a moving light source
\n<\/strong>Kaltashov, A.*, Parameshwar, P.K.*, Lin, N.*, Moraes, C., Journal of Micromechanics and Microengineering<\/em><\/span> [pdf] [SI] [link<\/a>]<\/td>\n<\/tr>\n
<\/td>\n[65].<\/td>\nThe DNMT1 inhibitor GSK-3484862 mediates global demethylation in murine embryonic stem cells
\n<\/strong>Portilho, N.A., Saini, D., Hossain, I., Sirois, J., Moraes, C., Pastor W.A.,\u00a0Epigenetics and Chromatin<\/em>\u00a0<\/span>(in press) [pdf] [SI] [link<\/a>]
\n<\/strong><\/td>\n<\/tr>\n
\"\"<\/td>\n[64].<\/td>\nDisease-specific extracellular matrix composition regulates placental trophoblast fusion efficiency<\/strong>
\nParameshwar, P.K., Sagrillo-Fagundes, L., Fournier, C., Girard, S., Vaillancourt C., Moraes, C., Biomaterials Science<\/em><\/span>,<\/span> DOI: 10.1039\/D1BM00799H (2021) [pdf] [SI] [link<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[63].<\/td>\nRevisiting tissue tensegrity: biomaterial-based approaches to measure forces across the length scales
\n<\/strong>Boghdady, C-M., Kalashnikov, N., Mok, S., McCaffrey, L., Moraes, C.,\u00a0APL Bioengineering<\/em><\/span> 5<\/b>, 041501 (2021) [pdf<\/a>] [link<\/a>]\u00a0 *Selected as a featured article by the journal editors<\/td>\n<\/tr>\n
\"\"<\/td>\n[62].<\/td>\nBioprintable, stiffness-tunable collagen-alginate microgels for increased throughput 3D cell culture studies
\n<\/strong>Ort, C.A., Chen, Y., Ghagre, A., Ehrlicher, A.J., Moraes, C.,\u00a0ACS Biomaterials Science &<\/em><\/span> Engineering<\/span>, <\/em>DOI: 10.1021\/acsbiomaterials.1c00129 (2021) [pdf] [SI] [link<\/a>]
\n<\/strong><\/td>\n<\/tr>\n
\"\"<\/td>\n[61].<\/td>\nArchitectural control of metabolic plasticity in epithelial cancer cells<\/strong>
\nAl-Masri, M., Paliotti, K., Tran, R., Halaoui, R., Lelarge, V., Chatterjee, S., Wang, L-T., Moraes, C., McCaffrey, L. Communications Biology<\/em><\/span> 4, 371 (2021) [link<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[60].<\/td>\nOxygenation as a driving factor in epithelial differentiation at the air-liquid interface
\n<\/strong>Kouthouridis, S., Goepp, J., Martini, C., Matthes, E., Hanrahan, J.W., Moraes, C., Integrative Biology<\/em><\/span>\u00a0<\/em>13, (3) p61-72 (2021) [pdf] [link<\/a>]
\n<\/strong><\/td>\n<\/tr>\n
\"\"<\/td>\n[59].<\/td>\nAccessible dynamic micropatterns in monolayer cultures via modified desktop xurography<\/strong>
\nTran, R., Hoesli, C.A*., Moraes, C.* Biofabrication<\/em><\/span> 13 025003 (2021) [pdf] [SI] [link<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[58].<\/td>\nDisentangling the fibrous microenvironment: designer culture models for improved drug discovery<\/strong>
\nOrt, C.A., Lee, W., Kalashnikov N., Moraes, C. Expert Opinion on Drug Discovery<\/em><\/span>\u00a020 (<\/span>8),<\/span> DOI: 10.1080\/17460441.2020.1822815 (2021)\u00a0<\/span> [pdf<\/a>] [link<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[57].<\/td>\nDevelopmentally-inspired biomimetic culture models to produce functional islet-like cells from pluripotent precursors<\/strong>
\nTran., R., Moraes, C*, Hoesli, C.A.* Frontiers in Bioengineering and Biotechnology<\/em><\/span> 8:583970 (2020) [pdf<\/a>] [link<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[56].<\/td>\nMapping cellular-scale internal mechanics in 3D tissues with thermally responsive hydrogel probes<\/strong>
\nMok, S., Al Habyan, S., Ledoux, C., Lee, W., Macdonald, K.N., McCaffrey, L., Moraes, C. Nature Communications<\/em><\/span> 11<\/span>,<\/span> 4757 (2020)<\/span> [link<\/a>] [SI<\/a>]
\n[in the media: McGill NewsRoom<\/a>; en Francais<\/a>; McGill Tribune<\/a>; altmetric<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[55].<\/td>\nHydrophilic Mechano-Bactericidal nanopillars require external forces to rapidly kill bacteria<\/strong>
\nValiei, A., Lin, N., Bryche, J.F., McKay, G., Canv, M., Charette, P.G., Nguyen, D., Moraes, C*, Tufenkji, N*\u00a0Nano Letters<\/em><\/span> 20 (<\/span>8),<\/span>\u00a05720\u20135727<\/span> (2020) [pdf<\/a>] [SI<\/a>] [link<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[54].<\/td>\nMechanobiological regulation of placental trophoblast fusion and function through extracellular matrix rigidity
\n<\/strong>Ma, Z., Sagrillo-Fagundes, L., Mok, S., Vaillancourt, C., Moraes, C.,\u00a0Scientific Reports<\/em><\/span> 10,\u00a0 5837<\/span>\u00a0(2020<\/span>) [pdf<\/a>] [link<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[53].<\/td>\nEnhanced differentiation of pluripotent stem cell-derived pancreatic progenitors using confined micropatterned cultures
\n<\/strong>Tran, R., Moraes, C.*, Hoesli, C.A.*,\u00a0Scientific Reports<\/em><\/span> 10:1190 (2020) [pdf<\/a>] [SI<\/a>] [link<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[52].<\/td>\nBiomimetic micropatterned adhesive surfaces to mechanobiologically regulate placental trophoblast fusion<\/strong>
\nMa, Z., Fagundes, L.S., Tran, R., Parameshwar, P.K., Kalashnikov, N., Vaillancourt, C., Moraes, C., ACS Applied Materials & Interfaces<\/em><\/span> 2019 [pdf<\/a>] [link<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[51].<\/td>\nFunctional redundancy between Beta1 and Beta3 Integrin in Activating the IR\/Akt\/mTORC1 signaling axis to promote ErbB2-Driven Breast Cancer<\/strong>
\nBui, T., Rennhack, J., Mok, S., Ling, C., Perez, M., Roccamo J., Andrecheck, ER, Moraes, C., Muller W.J. Cell Reports<\/em><\/span> 29 (3) 589-602 2019 [link<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[50].<\/td>\nThe W-Model: A pre-college design pedagogy for solving wicked problems<\/strong>
\nMoraes, C.\u00a7<\/sup>, Blain-Moraes, S.\u00a7<\/sup>, Morell-Tomassoni, S., Gorbet, R.\u00a0International Journal of Technology and Design Education<\/em><\/span> 2019 [pdf<\/a>] [link<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[49].<\/td>\nRobust and precise wounding and analysis of engineered contractile tissues.
\n<\/strong>Dubois, S.J. \u00a7<\/sup>, Kalashnikov, N. \u00a7<\/sup>, Moraes, C. Tissue Engineering C <\/em><\/span>2019 [pdf<\/a>] [SI<\/a>] [link<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[48].<\/td>\nMagnetic microboats for floating, stiffness tunable, air liquid interface epithelial cultures\u00a0<\/strong>
\nChandrasekaran, A., Kouthouridis, S., Lee, W., Lin, N., Ma, Z., Turner, J.M., Hanrahan, J.W., Moraes, C., Lab on a Chip<\/em><\/span> 2019 DOI:10.1039\/c9lc00267g\u00a0 [pdf<\/a>] [SI<\/a>] [link<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[47].<\/td>\nMicropocket hydrogel devices for all-in-one formation, assembly, and analysis of aggregate-based tissues
\n<\/strong>Zhao, L., Mok, S., Moraes, C., Biofabrication<\/em><\/span> 2019 DOI: 10.1088\/1758-5090\/ab30b4 [pdf<\/a>] [SI<\/a>] [link<\/a>]
\n<\/strong><\/td>\n<\/tr>\n
\"\"<\/td>\n[46].<\/td>\nDynamic bioreactors with integrated microfabricated devices for mechanobiological screening
\n<\/strong><\/strong>Beca, B.M., Sun, Y., Wong, E., Moraes, C*.<\/strong>, Simmons, C.A.* Tissue Engineering C<\/em><\/span> 2019 [pdf<\/a>] [link<\/a>]<\/span><\/td>\n<\/tr>\n
\"\"<\/td>\n[45].<\/td>\nMorphodynamic tissues via integrated programmable shape memory actuators<\/strong>
\nKalashnikov, N., Moraes, C., Advanced Functional Materials<\/span><\/em> 2019<\/span>, <\/em>1903327 [pdf<\/a>] [SI<\/a>] [link<\/a>]<\/span><\/td>\n<\/tr>\n
\"\"<\/td>\n[44].<\/td>\nMicrofluidic Shear Assay to Distinguish between Bacterial Adhesion
\nand Attachment Strength on Stiffness-Tunable Silicone Substrates
\n<\/strong>Siddiqui, S., Chandrasekaran, A., Lin, N., Tufenkji, N., Moraes, C., Langmuir<\/em><\/span> 2019, DOI:10.1021\/acs.langmuir.9b00803.\u00a0 [pdf<\/a>] [SI<\/a>] [link<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[43].<\/td>\nDispersible hydrogel force sensors reveal patterns of solid mechanical stress in multicellular spheroid cultures
\n<\/strong>Lee, W., Kalashnikov, N., Mok, S., Halaoui, R., Kuzmin, E., Putnam, A.J., Takayama, S., Park, M., McCaffrey L., Zhao, R., Leask, R.L., Moraes, C.,\u00a0Nature Communications<\/em><\/span>\u00a0<\/em>2019, 10:144.\u00a0 [pdf<\/a>] [SI<\/a>] [link<\/a>]
\n[In the press: McGill NewsRoom<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[42].<\/td>\nKibra (WWC1) is a metastasis suppressor gene affected by chromosome 5q loss in human triple negative breast cancers.<\/strong>
\nKnight JF, Sung V, Kuzmin E, Couzens A, de Verteuil DA, Johnson RM, Gruosso T, Lee W, Saleh SM, Zuo D, Guiot MC, Davis RR, Zhao H, Gregg JP, Moraes C,<\/strong> Gingras AC, Park\u00a0 M., Cell Reports<\/em><\/span> 2018, 22<\/strong> (12) p. 3191-32015 [link<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[41].<\/td>\nNanodarts, nanoblades, and nanospikes: Mechano-bactericidal nanostructures and where to find them
\n<\/strong>Lin, N., Berton, P., Moraes, C., Rogers, R.D., Tufenkji, N., Advances in Colloid and Interface Science<\/em><\/span>, 2018, 252<\/strong>, p. 55-68 [pdf<\/a>]<\/td>\n<\/tr>\n
\"\"<\/a><\/td>\n[40].<\/td>\nDispersible oxygen microsensors map oxygen gradients in three-dimensional cell cultures
\n<\/strong>Lesher-Perez, S.C., Kuo, C-H., Leung, B.M., Kim, G-H., Mong, S., Kojima, T., Moraes, C., Thouless, M.D., Luker, G.D., Takayama, S.,\u00a0Biomaterials Science<\/em><\/span>, 2017 [pdf<\/a>]
\n<\/strong><\/td>\n<\/tr>\n
\"\"<\/a><\/td>\n[39].<\/td>\nThermal scribing to prototype plastic microfluidic devices, applied to study the formation of neutrophil extracellular traps
\n<\/strong>Chandrasekaran, A., Kalashnikov, N., Rayes, R., Wang, C., Spicer, J., Moraes, C.,\u00a0Lab on a Chip<\/em><\/span> 2017, 17<\/strong>, 2003 – 2012 [pdf<\/a>] [SI<\/a>] [link<\/a>]<\/td>\n<\/tr>\n
\"\"<\/a><\/td>\n[38].<\/td>\nBuilding an experimental model of the human body with non-physiological parameters
\n<\/strong>Labuz J.M., Moraes, C., Mertz, D., Leung, B.M., Takayama, S. \u00a0Technology\u00a0<\/em><\/span>2017, 05 (1), 42-59 [pdf<\/a>] [link<\/a>]
\n<\/strong><\/td>\n<\/tr>\n
\"\"<\/td>\n[37].<\/td>\nGotta catch ’em all: the microscale quest to understand cancer biology<\/strong>
\nMa., Z., Moraes, C.,\u00a0Integrative Biology<\/em><\/span>, 2016,\u00a0DOI: 10.1039\/C6IB90045C \u00a0[Research Highlight – link<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[36].<\/td>\nMicrofluidics in Microbiology: Putting a Magnifying Glass on Microbes
\n<\/strong>Siddiqui, S.K., Tufenkji, N., Moraes, C.,\u00a0Integrative Biology<\/span>,<\/em> 2016, 8, 914-917 [Research Highlight – link<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[35].<\/td>\nStem Cells: to be born great, achieve greatness, or have greatness thrust upon them?<\/strong>
\nTran, R., Hoesli, C.A., Moraes, C.,\u00a0Integrative Biology<\/u><\/em>, DOI: 10.1039\/c6ib90021f [Research Highlight – link<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[34].<\/td>\nHave microfluidics delivered for drug discovery?<\/strong>
\nChandrasekaran, A., Abduljawad, M., Moraes, C.,\u00a0Expert Opinion on Drug Discovery<\/em>\u00a0<\/span>2016\u00a0DOI: 10.1080\/17460441.2016.1193485 [pdf<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[33].<\/td>\nNext generation tools to accelerate the synthetic biology process
\n<\/strong>Shih, S.C.C., Moraes, C. Integrative Biology<\/em><\/span>2016\u00a0DOI: 10.1039\/c6ib90017h [Research Highlight – link<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[32].<\/td>\nThinking big by thinking small: advances in mechanobiology across the length scales.
\n<\/strong>Mok, S., Moraes, C.,\u00a0Integrative Biology<\/em><\/span> 2016,\u00a08, 262-266. [Research Highlight – link<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[31].<\/td>\nGetting there is half the battle: recent advances in delivering therapeutics.
\n<\/strong>Lesher-Perez, S.C., Segura, T., Moraes, C.,\u00a0Integrative Biology<\/em><\/span> 2016. DOI:\u00a010.1039\/C5IB90052B [Research Highlight – link<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[30].<\/td>\nMaking it stick: the role of structural design in implantable technologies.
\n<\/strong>Lee, W., Leask, R.L., Moraes, C.,\u00a0Integrative Biology<\/span><\/em>2015. \u00a0DOI:\u00a010.1039\/C5IB90041G [Research Highlight – link<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[29].<\/td>\nPatients are a virtue: advances in microengineered systems for clinical applications.
\n<\/strong>Young, E.W.K., Moraes, C. \u00a0Integrative Biology<\/em><\/span> 2015. \u00a0DOI: \u00a010.1039\/C5IB90031J \u00a0[Research Highlight – link<\/a>]<\/td>\n<\/tr>\n
\"28thumb_supersoft\"<\/td>\n[28].<\/td>\nSupersoft lithography: Candy-based fabrication of soft silicone microstructures.
\n<\/strong>Moraes, C., Labuz, J.M., Shao, Y., Fu, J., Takayama, S.\u00a0Lab on a Chip<\/em><\/span> 2015. \u00a0DOI: 10.1039\/C5LC00722D [pdf<\/a>] [SI<\/a>] [link<\/a>]\u00a0 [News: \u00a0The Sweet Smell of Science<\/a>, U. Michigan Engineering\u00a0Youtube video<\/a>; Michigan Daily<\/a>; PopSci.com<\/a>; Smithsonian Magazine<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[27].<\/td>\nBetween a rock and a soft place: recent progress in understanding matrix mechanics. \u00a0<\/strong>Moraes, C.,\u00a0Integrative Biology<\/em><\/span> 2015 [Research Highlight – link<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[26].<\/td>\nLive long and prosper: the enterprise of understanding diseased epithelium.
\n<\/strong>Horowitz, A., Moraes, C. \u00a0Integrative Biology<\/em><\/span> 2015 7, 494-497 [Research Highlight –\u00a0link<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[25].<\/td>\nThe Discovery Channel: microfluidics and microengineered systems in drug screening.
\n<\/strong>Moraes, C.,\u00a0Integrative Biology<\/em><\/span>\u00a0<\/em>2015 7, 285-288 [Research Highlight –\u00a0link<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[24].<\/td>\nMicro, Soft, Windows: Integrating super-resolution viewing capabilities into soft lithographic devices.<\/strong>
\nMoraes, C., Integrative Biology<\/em><\/span> 2015, 7 (1) 10-13 [Research Highlight –\u00a0link<\/a>]<\/td>\n<\/tr>\n
\"23thumb_JALA\"<\/td>\n[23].<\/td>\nMicroscale 3D collagen cell culture assays in conventional flat-bottom 384-well plates.
\n<\/strong>Leung, B.M.\u00a7, Moraes, C.\u00a7, Cavnar, S.P., Luker, K.E., Luker, G.D., Takayama, S.\u00a0Journal of Laboratory Automation<\/em><\/span>\u00a0DOI: 10.1177\/2211068214563793 [pdf<\/a>][SI<\/a>]<\/td>\n<\/tr>\n
\u00a0\"22thumb_3Dmig\"<\/td>\n[22].<\/td>\nSurface-templated hydrogel patterns prompt matrix-dependent migration of breast cancer cells towards chemokine-secreting cells.<\/strong>
\nKojima, T., Moraes, C., Cavnar, S.P., Luker, G.D., Takayama, S.\u00a0Acta Biomaterialia<\/em><\/span>\u00a0DOI: 10.1016\/j.actbio.2014.11.033 [pdf<\/a>][SI<\/a>]<\/td>\n<\/tr>\n
\"21thumb_spheroids\"<\/td>\n[21].<\/td>\nMedia additives to promote spheroid circularity and compactness in hanging drop platforms
\n<\/strong>Leung, B.M., Lesher-Perez, S.C., Matsuoka, T., Moraes, C., Takayama, S. \u00a0Biomaterials Science<\/em><\/span>\u00a0DOI: 10.1039\/C4BM00319E \u00a0[pdf<\/a>]
\n<\/strong><\/td>\n<\/tr>\n
\"20thumb_hPDMScracks\"<\/td>\n[20].<\/td>\nFracture-based fabrication of normally-closed, adjustable and fully reversible micro-scale fluidic channels.
\n<\/strong>Kim, B.C.\u00a7, Moraes, C.\u00a7, Huang, J., Matsuoka, T., Thouless, M.D., Takayama, S. Small<\/em><\/span>\u00a010 (19) pp. 4020-4029. [pdf<\/a>][SI<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[19].<\/td>\nDefined topologically-complex protein matrices to manipulate cell shape via three-dimensional fiber-like patterns.<\/strong>
\nMoraes, C., Kim, B.C., Zhu, X., Mills, K.L., Dixon, A.R., Thouless, M.D., Takayama, S. Lab on a Chip<\/span>\u00a0<\/em>14, pp.\u00a02191-2201 (2014).\u00a0[pdf<\/a>][SI<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[18].<\/td>\nBiological applications enabled by fracture-guided micro and nanofabrication<\/strong>
\nKim, B.C., Moraes, C., Huang, J., Thouless, M.D., Takayama, S. Biomaterials\u00a0Science <\/em><\/span>2, 288 (2014)\u00a0[pdf<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[17].<\/td>\nGuided fracture of films on soft substrates to create micro\/nano-feature arrays with controlled periodicity
\n<\/strong> Kim, B.C., Matsuoka, T., Moraes, C., Huang, J., Thouless, M.D., Takayama, S.\u00a0Scientific Reports<\/i><\/span>\u00a03, 3027 (2013). [pdf<\/a>]<\/td>\n<\/tr>\n
\"16thumb_contraction\"<\/td>\n[16].<\/td>\nAqueous two-phase printing of contractile collagen microgels<\/strong>
\nMoraes, C., Simon, A.B., Putnam, A.J., Takayama, S.\u00a0Biomaterials<\/i><\/span>\u00a034 (37), pp. 9623-31 (2013). [pdf<\/a>] [SI<\/a>] [Highlight: Genetic Engineering and Biotechnology<\/a>]<\/td>\n<\/tr>\n
\"15thumb_epigenetics\"<\/td>\n[15].<\/td>\nMicro- and nanofluidic technologies for epigenetic profiling<\/strong>
\nMatsuoka, T., Kim, B.C., Moraes, C., Hun, M., Takayama, S. Biomicrofluidics<\/i><\/span>\u00a07, 041301\u00a0(2013). [pdf<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[14].<\/td>\nOn being the right size: scaling effects in designing a human-on-a-chip<\/strong>
\nMoraes, C.\u00a0\u00a7<\/sup>, Labuz M.J.\u00a0\u00a7<\/sup>, Leung, B.M.\u00a0\u00a7<\/sup>, Inoue, M., Chun, T-H., Takayama, S. Integrative Biology<\/span>\u00a0<\/i>5 (9), pp. 1149-61.\u00a0(2013). [pdf<\/a>] [Highlight: Lab on a Chip<\/a>]<\/td>\n<\/tr>\n
\"13thumb_1Dcracks\"<\/td>\n[13].<\/td>\nOne-dimensional patterning of cells in silicone wells via compression-induced fracture
\n<\/strong>Dixon, A.R., Moraes, C., Csete, M., Thouless, M.D., Takayama, S. Journal of Biomedical Materials Research A<\/i><\/span>\u00a0102(5), pp. 1361-9\u00a0(2013). [pdf<\/a>]<\/td>\n<\/tr>\n
\"12thumb_bulge\"<\/td>\n[12].<\/td>\nMicrodevice array-based identification of distinct mechanobiological response profiles in layer-specific valve interstitial cells<\/strong>
\nMoraes, C.\u00a0\u00a7<\/sup>, Likhitpanichkul, M.\u00a0\u00a7<\/sup>, Lam, C.J., Beca, B.M., Sun, Y., Simmons, C.A.\u00a0Integrative Biology<\/i><\/span>\u00a05 pp. 673-80.\u00a0(2013) [pdf<\/a>] [SI<\/a>]<\/td>\n<\/tr>\n
\"11thumb_soapBubbles\"<\/td>\n[11].<\/td>\nPop culture: a soap-bubble based framework for nanoeducation outreach<\/strong>
\nMoraes, C. International Journal of Engineering Education<\/i><\/span>\u00a028(5) pp. 1088-94\u00a0(2012) [pdf<\/a>]<\/td>\n<\/tr>\n
\"10thumb_OoCReview\"<\/td>\n[10].<\/td>\nOrgans on a chip: focus on compartmentalized microdevices<\/strong>
\nMoraes, C.\u00a0\u00a7<\/sup>, Mehta, G.\u00a0\u00a7<\/sup>, Lesher-Perez, S.\u00a0\u00a7<\/sup>, Takayama, S. Annals of Biomedical Engineering<\/span>\u00a0<\/i>40(6) pp. 1211-27 (2011) [pdf<\/a>]<\/td>\n<\/tr>\n
\"09thumb_Micromanage\"<\/td>\n[9].<\/td>\n(Micro) managing the mechanical microenvironment<\/strong>
\nMoraes, C., Sun, Y., Simmons, C.A. Integrative Biology<\/i><\/span>\u00a03, pp. 959-971 (2011). [pdf<\/a>]\u00a0[Featured: Integrative Biology’s Top 2013 Cited Papers<\/a>]<\/td>\n<\/tr>\n
\"08thumb_SemiConfined\"<\/td>\n[8].<\/td>\nSemi-confined compression of microfabricated biomaterial constructs<\/strong>
\nMoraes, C., Zhao, R., Likhitpanichkul, M., Simmons, C.A., Sun, Y. Journal of Micromechanics and Microengineering<\/i><\/span>\u00a0(21) 054014\u00a0(2011). [pdf<\/a>]<\/td>\n<\/tr>\n
\"06thumb_singleCellDep\"<\/td>\n[7].<\/td>\nSingle cell deposition and patterning with a robotic system<\/strong>
\nLu, Z.\u00a7<\/sup>, Moraes, C.\u00a7<\/sup>, Ye, G., Simmons, C.A., Sun, Y. PLoS ONE<\/i><\/span>,\u00a0 5, e13542\u00a0(2010). [pdf<\/a>][correction<\/a>]<\/td>\n<\/tr>\n
\"07thumb_JOVE\"<\/td>\n[6].<\/td>\nMicrofabricated platforms for mechanically dynamic cell culture<\/strong>
\nMoraes, C., Sun, Y., Simmons, C.A. Journal of Visualized Experiments<\/i><\/span>\u00a046 (2) e2224 doi:10.3791\/2224\u00a0(2010). [link<\/a>]<\/td>\n<\/tr>\n
\"05thumb_iMAchip\"<\/td>\n[5].<\/td>\nAn undergraduate lab (on-a-chip):\u00a0 Probing single cell mechanics on a microfluidic platform<\/strong>
\nMoraes, C., Wyss, K., Brisson, E., Keith, B.A., Sun, Y., Simmons, C.A.\u00a0Cellular and Molecular Bioengineering<\/i><\/span>\u00a03(3), pp. 319-330\u00a0(2010). [pdf<\/a>] [labManual<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[4].<\/td>\nMicrofabricated arrays for high-throughput screening of cellular response to cyclic substrate deformation<\/strong>
\nMoraes, C., Chen, J-H., Sun, Y., Simmons, C.A. \u00a0Lab on a Chip<\/i><\/span>\u00a010(2) pp. 227-34\u00a0(2010). [pdf<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[3].<\/td>\nA microfabricated platform for high throughput unconfined compression of micropatterned biomaterial arrays
\n<\/strong>Moraes, C., Wang, G., Sun, Y., Simmons, C.A. Biomaterials\u00a0<\/i>31(3) pp. 557-84\u00a0(2010). [pdf<\/a>]<\/td>\n<\/tr>\n
\"\"<\/td>\n[2].<\/td>\nIntegrating polyurethane culture substrates into poly(dimethylsiloxane) microdevices
\n<\/strong>Moraes, C., Kagoma, Y.K., Beca, B.M., Tonelli-Zasarsky, R.L.M., Sun, Y., Simmons, C.A. \u00a0Biomaterials<\/i>\u00a030(28) pp. 5241-50 (2009). [pdf<\/a>]<\/td>\n<\/tr>\n
\"01thumb_alignment\"<\/td>\n[1].<\/td>\nSolving the shrinkage-induced PDMS registration problem in multilayer soft lithography<\/strong>
\nMoraes, C., Sun, Y., Simmons, C.A. Journal of Micromechanics and Microengineering<\/i>\u00a0(19) 065015 (2009). [pdf<\/a>]<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

<\/p>\n

<\/h2>\n

Book Chapters<\/strong><\/h2>\n

[8].\u00a0 Tran, R., Moraes, C., Hoesli, C.A., \u201cProduction of pluripotent stem cell-derived pancreatic cells by manipulating cell-surface interactions\u201d, Advanced Materials, 2019, ISBN: 978-3-11-053765-9, in press.<\/p>\n

[7].\u00a0 Cooper, S., Moraes, C. \u00a7<\/sup>, Leask, R.L.,\u00a7<\/sup> \u201cBiological Considerations: Cardiovascular 3D systems\u201d in \u201cEngineering 3D Tissue Test Systems<\/em>\u201d, Taylor and Francis.<\/p>\n

[6]. \u00a0 \u00a0 Leung, B.M., Labuz, J.M., Moraes, C., Takayama, S., 2015. \u00a0“Chapter 9: \u00a0Bioprinting using aqueous two phase systems” in Essentials of 3D Biofabrication and Translation,\u00a0<\/i>Elsevier ISBN:\u00a0978-0128009727<\/p>\n

[4]. \u00a0 \u00a0 \u00a0 MacQueen, L., Moraes, C., Sun, Y., Simmons, C.A., 2014. \u00a0“Chapter 16: Dynamic Mechanical Environments to Quantify and Control Cellular Dynamics” in\u00a0Cells, Forces and the Microenvironment\u00a0<\/em>Pan Stanford Publishing, ISBN (Hardcover): 978-981-4613-36-1 ISBN (eBook): 978-981-4613-37-8).<\/p>\n

[3].\u00a0\u00a0\u00a0\u00a0 Liu, J. \u00a7<\/sup><\/b>, Moraes, C. \u00a7<\/sup>, Lu, Z. \u00a7<\/sup>, Simmons, C.A., Sun, Y., 2012.\u00a0 \u201cChapter 23: Single cell deposition\u201d in Methods in Cell Biology<\/i>, 2012; 112:403-420, Elsevier.<\/p>\n

[2].\u00a0\u00a0\u00a0\u00a0 White, J., Douville, N., Moraes, C., Takayama, S., 2011.\u00a0 \u201cMicrofluidic approaches towards pulmonary tissue constructs\u201d, in Microfluidic Cell Culture Systems<\/i>, Chapter 10, Elsevier 2011 (ISBN: 978-1-4377-3459-1)<\/p>\n

[1].\u00a0\u00a0\u00a0\u00a0 Moraes, C., Sun, Y., Simmons, C.A., 2011.\u00a0 \u201cMicro and nano-technologies for studies in cellular mechanics and mechanobiology\u201d, in \u201cCellular and Biomolecular Mechanics and Mechanobiology<\/i>\u201d.\u00a0 Editor: Amit Gefen, Ph.D.; Book series: Studies in mechanobiology Tissue Engineering and Biomaterials, Vol 4, pp 145-175, DOI 10.1007\/8415_2010_24<\/p>\n

Other Contributions<\/strong><\/h2>\n

[2].\u00a0\u00a0\u00a0\u00a0 Moraes, C., Sun, Y., Simmons, C.A., 2010.\u00a0 \u201cConnector-less manipulation of small liquid volumes in microchannels\u201d in Chips & Tips, <\/i>(online supplement to Lab on a Chip<\/i>). [link<\/a>]<\/p>\n

[1].\u00a0\u00a0\u00a0\u00a0 Moraes, C., Simmons, C.A., Sun, Y., 2006.\u00a0 \u201cCell Mechanics Meets MEMS\u201d, Canadian Society of Mechanical Engineers Fall 2006 Bulletin. [pdf<\/a>]<\/p>\n

<\/div>","protected":false},"excerpt":{"rendered":"

Please note: Digital copies provided for personal use only. Citation information available via Google Scholar. Journal articles: \u00a7, *\u00a0 indicates equal authorship [94]. Heart-On-a-Chip with Integrated Ultrasoft Mechanosensors for Continuous Measurement of Cell- and Tissue-scale Contractility Mousavi, A., Boghdady, C-M.,<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-21","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/moraeslab.com\/cmed\/wp-json\/wp\/v2\/pages\/21","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/moraeslab.com\/cmed\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/moraeslab.com\/cmed\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/moraeslab.com\/cmed\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/moraeslab.com\/cmed\/wp-json\/wp\/v2\/comments?post=21"}],"version-history":[{"count":4,"href":"https:\/\/moraeslab.com\/cmed\/wp-json\/wp\/v2\/pages\/21\/revisions"}],"predecessor-version":[{"id":1776,"href":"https:\/\/moraeslab.com\/cmed\/wp-json\/wp\/v2\/pages\/21\/revisions\/1776"}],"wp:attachment":[{"href":"https:\/\/moraeslab.com\/cmed\/wp-json\/wp\/v2\/media?parent=21"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}